In these patients, serum calcium levels should be followed and renal function should be monitored.Ĭaltrate Plus 500 mg Chewable Tablets contain isomalt (E953). The risk of soft tissue calcification should be taken into account.ĭuring high dose therapy and especially during concomitant treatment with vitamin D and/or medications or nutrients (such as milk) containing calcium, there is a risk of hypercalcaemia and milk-alkali syndrome (hypercalcaemia, alkalosis and renal impairment) with subsequent kidney function impairment. Monitoring is especially important in patients on concomitant treatment with cardiac glycosides or diuretics (see 4.5), in patients with a high tendency to calculus formation, in cases of hypercalcaemia, or signs of impaired renal function.Ĭalcium carbonate should be used with caution in patients with hypercalcaemia or signs of impaired renal function and the effect on calcium and phosphate levels should be monitored. Caution should be exercised in patients with a history of renal calculi.ĭuring long-term treatment, serum calcium levels should be followed and renal function should be monitored through measurements of serum creatinine.
In renal insufficiency the tablets should be given only under controlled conditions for hyperphosphataemia.
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